The Division for Advancement and External Relations  

 
YEHUDA  TZFATI,   
Status : ACTIVE Birth place : RAMAT-GAN
Office Phone: 02-658-4902 Fax: 02-658-6975
E-Mail: tzfati@mail.huji.ac.il
U.R.L: http://tzfatid.wix.com/tzfati-lab
 
Department Faculty  
GENETICS FACULTY OF SCIENCE Dept. Description
 
Academic Degree   Institution Year
Ph.D. HEBREW UNIV. 1996
 
Academic Position   Year
ASSOC. PROFESSOR 2013
SENIOR LECTURER 2002
 
Research Interests
Telomerase, telomeres, RNA structure and function.
 
Research Projects
Three-dimensional RNA structure and the mechanism of action of
Genetic diseases of telomere dysfunction such as dyskeratosis
How telomeres control cell proliferation and prevent cancer.
The role of helicases in telomere structure and maintenance.
 
Selected Publications
Publication Title   Year
Unraveling the pathogenesis of Hoyeraal-Hreidarsson syndrome, a 2015
Inherited mutations in the helicase RTEL1 cause telomere 2013
Pyrimidine motif triple helix in the Kluyveromyces lactis 2013
The Trypanosoma brucei telomerase RNA (TER) homologue binds core 2013
Identification of Telomerase RNAs from filamentous fungi reveals 2013
"Poisoning" yeast telomeres distinguishes between redundant 2012
Telomerase RNA: Structure, function, and molecular mechanisms. 2012
Electron-transfer quenching of nucleic acid-functionalized 2011
DNAzyme-like activity of hemin-telomeric G-quadruplexes for the 2010
Optical, electrical and surface plasmon resonance methods for 2010
Identification and comparative analysis of telomerase RNAs from 2009
Diminished telomeric 3' overhangs are associated with telomere 2009
The 5' arm of Kluyveromyces lactis telomerase RNA is critical 2008
Pseudoknot structures with conserved base triples in telomerase 2007
A triple helix within a pseudoknot is a conserved and essential 2007
Telomerase core components protect Candida telomeres from 2007
A critical three-way junction is conserved in budding yeast and 2007
A universal telomerase RNA core structure includes structured 2004
A novel pseudoknot element is essential for the action of a 2003
A template-proximal RNA paired element contributes to 2003
A bulged stem tethers Est1p to telomerase RNA in budding yeast. 2002
Template boundary in a yeast telomerase specified by RNA 2000

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