The Division for Development and Public Relations     MICHAEL  SCHLESINGER,  LADY DAVIS PROF EMERITUS OF EXPERIMENTAL MEDICINE AND CANCER  Status : EMERITUS Birth place : WORMS Office Phone: 02-675-8334 Fax: 02-641-4583 E-Mail: mschlesi@md.huji.ac.il U.R.L: http://research.ekmd.huji.ac.il/researchers.asp?id=248   Department Faculty   HUMPHREY CENTER FOR EXPERIMENTAL FACULTY OF MEDICINE Dept. Description DEVELOPMENTAL BIOLOGY AND CANCER RESEARC FACULTY OF MEDICINE Dept. Description   Academic Degree   Institution Year M.D. HEBREW UNIV. 1958   Academic Position   Year EMERITUS 2001 PROFESSOR 1973 ASSOC. PROFESSOR 1969 SENIOR LECTURER 1966 LECTURER 1965   Administrative Position   From To Vice-President 1977 1982 Chair, Authority for R&D 1977 1982 Chair, Hubert H. Humphrey Center for Experimental Medicine & Can- 1987 1990 cer Research Chair, Paul Ehrlich Center for the Study of Leukemic & Normal Wh- 1988 1998 ite Blood Cells Acting Vice-President for R&D 1994 1995   External Academic Positions NIH Fellow: Duke Univ., 1963; Sloan-Kettering Inst. for Can- cer Research, N.Y., 1964 Visiting Prof.: Duke Univ., 1969; Mt. Sinai Med. School, 19- 75, 1982, 1992-93; Pittsburg Univ., 1990-91 Memberships and Fellowships: Int'l Transplantation Soc.; N.Y. Acad. of Sci. Awards and Honors: Green Honors Scholarship, Oklahoma Med. Research Foundation- , 1987   Research Interests Subpopulations of lymphocytes in man. Lymphocyte subpopulations in patients with autoimmune disease and with acquired immunodeficiency syndrome (AIDS). Characterization of cell surface markers in leukemias and lymphomas. Analysis of the dynamics of cell surface expression. The transfer of antigens between cells. Development of new anti-cancer compounds. Dielectric properties of human leukemic cells.   Research Projects Regulation of the expression of differentiation antigens on B-cells: Transfer of antigens from activated T-cells to B-cells: Immunological changes in AIDS:   Selected Publications Publication Title   Year Immunological assessment of familial tinea corporis. 2008 A cannabinoid anticancer quinone, HU-331, is more potent and 2007 HU-331, a novel cannabinoid-based anticancer topoisomerase II 2007 A cannabinoid quinone inhibits angiogenesis by targeting 2006 Synthesis and antitumor activity of quinonoid derivatives of 2004 Mucosal (SIgA) and serum (IgG) immunologic resonses in young 2004 Mucosal [SIgA] and serum [IgG] immunologic responses in the 2002 Replication of HIV-1 deleted Nef mutants in chronically immune 2002 Correlation between the expression of CD4 and the level of CD4 2002 Hyposialated 185 kDa CD45RA+molecules attain a high 2002 Serum and mucosal immunologic responses in children following 2001 Regulation of the expression of cd45 isoforms in the farage 2001 Study of normal and malignant white blood cells by time domain 2001 Suppressors of cancer cell proliferation from fig (Ficus carica) 2001 B-lymphocytes in CLL and NHL differ in the mRNA splicing pattern 2000 Natural killer (NK) and T cell-associated surface marker 2000 3-m-bromoacetylamino benzoic acid ethyl ester: A new 2000 Monocytes confer CD14 antigenicity on activated lymphocytes. 1999 Detection of minimal residual disease (MRD) after bone marrow 1999 Somatic mutations and intraclonal variations in the rearranged 1999 Time domain dielectric spectroscopy study of human cells - II. 1999 Lymphocyte subset profile of young healthy children residing in 1999 Time domain dielectric spectroscopy study of human cells. II. 1999 Tumorigenicity and immunogenicity in a murine model of B-cell 1998 Lymphocyte subsets in human tonsils: The effect of age and 1998 The down-modulation of CD4 induced by the GM1 ganglioside is 1998 Enhanced lymphoid cell recovery after bone marrow 1998 Activated human T-cells bestow T-cell antigens to non-T-cells by 1998 Antibodies to cytomegalo and Epstein-Barr viruses in human 1998 The CD38 lymphocyte differentiation marker: New insight into its 1997 Pathways controlling the expression of surface CD21 (CR2) and 1997 The effect of dental alloys on sub populations of lymphocytes in 1997 HIV infection and AIDS in Jerusalem: a microcosm of illness in 1996 The expression of CD8 on B-lymphocytes in HIV-infected 1996 Time domain dielectric spectroscopy study of human cells. 1. 1996 Preferential cytotoxic effect of Newcastle disease virus on 1996 Analysis of myeloid and lymphoid markers on the surface and in 1996 HIV infection and AIDS in Jerusaem: A microcosm of illness in 1996 The mechanism of interleukin-4 induced down-regulation of CD38 1996 In vitro activation leads to the binding of T-cell markers to 1995 Increased expression of activation markers on CD8 lymphocytes in 1995 Prevalence of viral antibodies in gingival cervicular fluid. 1994 Kinetics of the pleiotropic effect of IL-4 on surface properties 1994 The effects of interleukin-4 on the cell cycle of a human B-cell 1994 A distinctive form of soluble CD8 is secreted by stimulated CD8+ 1994 Myelomonocytic antigens are rarely expressed on B-lymphocytic 1993 Psychological stress and NK cells among members of a communal 1993 Peripheral blood lymphocyte subsets in infants with diarrhea 1993 Farage, a new early B cell lymphoma cell line with trisomy II. 1992 The effect of heating on the expression and function of CD2 1991 The Thy-1 antigen. 1991 The relationship between psychosocial measures and cellular 1991 Expression of CD11a (LFA-1) on chronic lymphocytic leukemia and 1991 The impact of stressful life events on natural killer cells. 1991 Changes in the level of soluble CD-2 molecules in the serum of 1990 Modulation of the expression of CD4 on HL-60 cells by exposure 1989 Treatment of mouse thymus cells with phosphatidylinositol- 1989 The function of Thy-1. 1989 Psychological factors in cell-mediated immunity. 1988   © All rights reserved to The Hebrew University of Jerusalem